Fluorescently Labeled Gold Nanoparticles for Cellular Uptake

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Fluorescently Labeled Gold Nanoparticles for Cellular Uptake
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Creative Diagnostics offers a series of fluorophore labeled gold nanoparticles which show efficient cell uptake. Colloidal and intracellular gold nanoparticles can be validated by confocal microscopy. Most importantly, they are large enough that they don't need to be grown through silver or gold growth methods after the fact as post treatments are known to destroy cell ultrastructure. These products show the potential for drug and oligo delivery to cells.

It is generally admitted that positive nanoparticles are more internalized by cells than neutral or negative nanoparticles, and it is well known that the strongly positive MUTAB ((11-Mercaptoundecyl)-N N N-trimethylammonium bromide) and MTAB ((16-mercaptohexadecyl)tri-methylammonium bromide) ligands lead to efficient cell uptake. Unfortunately because of their construct, there is no way to add fluorophores. Our DiagNano™ gold nanoparticles are coated with special cell uptake ligand which help to resolve that issue, and also the special cell uptake ligand design has reduced the overall size of the construct, making it more efficient at cell uptake. DiagNano™ Fluorophore Labeled Gold Nanoparticles for Cellular Uptake can be used for imaging cells as fluorescent probes and obtain good cell images, the DiagNano™ cell uptake line has five-fold higher uptake than common fluorophore labeled gold nanoparticles which have just polymer ligands. DiagNano™ Fluorophore Labeled Gold Nanoparticles for Cellular Uptake has potential applications in cancer diagnostics, studies, and immunoassays.

DiagNano™ Fluorophore Labeled Gold Nanoparticles for Cellular Uptake are available with the following fluorophores, customers can choose appropriate one for their imaging system.

IRDye 800Alexa Fluor 750Alexa Fluor 680Cy5.5
Dy 650Alexa Fluor 647Cy5Alexa Fluor 633
Alexa Fluor 594Dy594Texas RedAlexa Fluor 546
Alexa Fluor 555Dy550Cy3Cy3.5
RhodamineFITCAlexa Fluor 488Dy488
AF405Dy405Dy488 


Cat. No.Product NameAbsorption MaxUnit SizeInquiry
GFL-10-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 10 nm, Cellular Uptake514-520 nm1 mLOnline inquiry
GFL-15-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 15 nm, Cellular Uptake514-520 nm1 mLOnline inquiry
GFL-20-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 20 nm, Cellular Uptake514-520 nm1 mLOnline inquiry
GFL-25-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 25 nm, Cellular Uptake514-520 nm1 mLOnline inquiry
GFL-30-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 30 nm, Cellular Uptake523 nm1 mLOnline inquiry
GFL-35-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 35 nm, Cellular Uptake526 nm1 mLOnline inquiry
GFL-40-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 40 nm, Cellular Uptake527 nm1 mLOnline inquiry
GFL-45-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 45 nm, Cellular Uptake529 nm1 mLOnline inquiry
GFL-50-CUDiagNano™ Fluorophore Labeled Gold Nanoparticles, 50 nm, Cellular Uptake531 nm1 mLOnline inquiry

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