The DiagNano™ silica magnetic particles are produced by hydrolysis of orthosilicates in the presence of magnetite and have a hydrophilic surface with terminal Si-OH-bonds and can easily be separated with conventional permanent magnets. They are extremely stable in organic solvents and at high temperatures.
Silica coating not only contributes to the improved stability and prolonged shelf-life due to inertness of silica, but also facilitates the surface functionalization by providing various active reacting groups, including OH, NH2, COOH, SH, N-hydroxysuccinimide (NHS) and epoxy for the covalent binding of proteins, antibodies, or other molecules. It can also be used for nucleic acids isolation and purification though the DNA/RNA-silica interaction method created by Boom et al. in 1990, with improved efficiency and simplified operation. The silica magnetic particles are also available with functional protein ligands (avidin, streptavidin, protein A, albumin) or biotin. They can be offered with the nickel(II) chelator nitrilotriacetic acid (NTA) or ready to use with the corresponding nickel complex (Ni-NTA) for the binding of histidine labeled proteins. The magnetic silica particles are available with a hydrophobic octadecyl (C18) surface, and can be delivered with an organic polymer shell (coreshell method) on request.

Cat. No.	Description	Surface	Diameter	Concentration	Unit Size	Add to basket
SMP-NM01	Silica Magnetic Particles	Hydroxyl	350 nm	25 mg/mL	10 mL
SMP-NM03	Silica Magnetic Particles	Amine	250 nm	10 mg/mL	10 mL
SMP-NM04	Silica Magnetic Particles	Carboxyl	250 nm	10 mg/mL	10 mL
SMP-NM05	Silica Magnetic Particles	Hydroxyl	250 nm	10 mg/mL	10 mL
SMP-NM06	Silica Magnetic Particles	Octadecyl (C18)	250 nm	25 mg/mL	10 mL
SMP-UM02	Silica Magnetic Particles	Hydroxyl	1.5 µm	50 mg/mL	10 mL
SMP-UM03	Silica Magnetic Particles	Amine	1.5 µm	50 mg/mL	10 mL
SMP-UM04	Silica Magnetic Particles	Carboxyl	1.5 µm	50 mg/mL	10 mL
SMP-UM05	Silica Magnetic Particles	Epoxy	1.5 µm	N/A	500 mg
SMP-UM06	Silica Magnetic Particles	NTA	1.5 µm	50 mg/mL	10 mL
SMP-UM07	Silica Magnetic Particles	NHS	1.5 µm	N/A	500 mg
SMP-UM08	Silica Magnetic Particles	Avidin	1.5 µm	10 mg/mL	2 mL
SMP-UM09	Silica Magnetic Particles	Streptavidin	1.5 µm	10 mg/mL	2 mL
SMP-UM10	Silica Magnetic Particles	Protein A	1.5 µm	10 mg/mL	2 mL
SMP-UM11	Silica Magnetic Particles	Albumin (BSA)	1.5 µm	10 mg/mL	5 mL
SMP-UM12	Silica Magnetic Particles	Biotin	1.5 µm	25 mg/mL	5 mL
SMP-UM13	Silica Magnetic Particles	Ni-NTA	1.5 µm	25 mg/mL	10 mL
SMP-UM14	Silica Magnetic Particles	Octadecyl (C18)	1.5 µm	N/A	500 mg
SMP-UM15	Silica Magnetic Particles	Hydroxyl	6 µm	50 mg/mL	10 mL
SMP-UM16	Silica Magnetic Particles	Amine	6 µm	50 mg/mL	10 mL

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