MagIso™ Dye-terminator Removal Kit, Sequencing (# WHK-C014) is designed for removal of unbound fluorescently-labelled dideoxy-ribonucleotides (ddNTPs) and salt from sequencing reactions with magnetic particles. This protocol can be performed directly in the thermal cycling plate. The kit contains an optimized magnetic particle solution to selectively bind sequencing extension products. Unincorporated dyes, nucleotides, salts and contaminants can be removed using a simple washing procedure. The MagIso™ Dye-terminator Removal Kit is amenable to a variety of automatization platforms since it requires no centrifugation, vacuum filtration or caustic solutions.