Absolute Mag™ Amine Magnetic Particles, Agarose Matrixs (# WHM-L087) are activated magnetic particles for coupling of amino containing ligands, e.g. proteins, antibodies and aptamers. After conjugation of the ligand without using any hazardous reagents or organic solvents, the magnetic particles can be used for affinity purification and immunoprecipitation.
|Q: What is the mechanism for the affinity binding between beads and proteins?|
|A: The coupling chemistry that is used to bind protein A, or custom proteins for WHM-L087, is proprietary, so we can’t disclose any details. The coupling takes place through activated groups on the beads and primary amine or thiol groups in the protein.|