{"id":324,"date":"2021-09-24T02:15:09","date_gmt":"2021-09-24T07:15:09","guid":{"rendered":"https:\/\/www.cd-bioparticles.com\/blog\/?p=324"},"modified":"2021-09-24T02:15:09","modified_gmt":"2021-09-24T07:15:09","slug":"contrast-agents-for-magnetic-resonance-imaging","status":"publish","type":"post","link":"https:\/\/www.cd-bioparticles.com\/blog\/magnetic-beads\/contrast-agents-for-magnetic-resonance-imaging\/","title":{"rendered":"Contrast Agents for Magnetic Resonance Imaging"},"content":{"rendered":"\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"682\" src=\"\/blog\/wp-content\/uploads\/2021\/09\/Magnetic-Resonance-Imaging-1024x682.jpg\" alt=\"Magnetic Resonance Imaging\" class=\"wp-image-325\" srcset=\"\/blog\/wp-content\/uploads\/2021\/09\/Magnetic-Resonance-Imaging-1024x682.jpg 1024w, \/blog\/wp-content\/uploads\/2021\/09\/Magnetic-Resonance-Imaging-300x200.jpg 300w, \/blog\/wp-content\/uploads\/2021\/09\/Magnetic-Resonance-Imaging-768x511.jpg 768w, \/blog\/wp-content\/uploads\/2021\/09\/Magnetic-Resonance-Imaging-120x80.jpg 120w, \/blog\/wp-content\/uploads\/2021\/09\/Magnetic-Resonance-Imaging.jpg 1269w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>Magnetic resonance imaging (MRI) is a scan that uses a\nstrong magnetic field and radio waves to generate detailed images of the inside\nof the body. <a href=\"https:\/\/www.cd-bioparticles.com\/s\/Magnetic-Resonance-Imaging-MRI_36.html\">MRI<\/a>\ncan be used to detect the brain tumors, traumatic brain injury, dysplasia,\nmultiple sclerosis, stroke, dementia, infection, and causes of headaches. It is\na noninvasive method that allows for fast and reproducible measurements of\nadipose tissue content in neonates with low intra- and intercoefficients of\nvariability.<\/p>\n\n\n\n<p>MRI is based on nuclear magnetic resonance (NMR), which was\nfirst documented in 1939 in a molecular beam by Isidor Rabi, who received the\nNobel Prize in Physics in 1944. In 1946, techniques were developed\nindependently by Felix Bloch and Edward Purcell that extended NMR to liquids\nand solids. Bloch and Purcell shared the Nobel Prize in Physics in 1952 for\nother important contributions to methods in magnetic resonance. It was not\nuntil 1973 that Paul Lauterbur devised a technique to create the first 2-D\nimage from NMR signals. This is now known as MRI. <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Which is better a CT scan or MRI?<\/li><\/ul>\n\n\n\n<p>Both MRI and computed tomography (CT) scans can\nview the internal structure of the body. However, CT scans are faster and can\nprovide pictures of tissues, organs, and bone structures. MRI is very good at\ncapturing images and helping doctors determine whether there are abnormal\ntissues in the body. MRI is more detailed in its images, and crucially, it\ndiffers from CT by producing excellent soft tissue contrast without harmful\nionizing radiation.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>What are contrast\nagents for MRI?<\/li><\/ul>\n\n\n\n<p>MRI is a non-invasive clinical imaging modality\nand has become widely used in the diagnosis and\/or staging of human diseases\naround the world. Some MRI examinations include the use of contrast agents. The\ncategorizations of currently available contrast agents have been described\naccording to their effect on the image, magnetic behavior and biodistribution\nin the body, respectively. In this field, superparamagnetic iron oxide\nparticles and soluble paramagnetic metal chelates are two main classes of\ncontrast agents for MRI. <\/p>\n\n\n\n<p>Gadolinium is the most famous MRI contrast agent. And iron\noxide nanoparticles are the most prominent probes in MRI because of their\ntunable properties, such as magnetic properties, size, and easy binding to\nbiomolecules. Iron oxide nanoparticles can also be combined with other imaging motifs\nsuch as fluorescent molecules and radioisotopes to create a multi-modal imaging\nsystem.<\/p>\n\n\n\n<p>With years of experience in the development of diagnostic\nand imaging contrast agents, CD Bioparticles\u2019 scientists can fine-tune physical\nparameters such as the size, shape, crystallinity, and magnetic properties of\nnanoparticles to improve their performance in MRI. In addition, Creative\nDiagnostics provides multi-modal imaging probes by combining iron oxide\nnanoparticles with fluorescent probes, PET probes, and ultrasound probes to\nimprove the quality of diagnosis.<\/p>\n\n\n\n<p>About the author <\/p>\n\n\n\n<p>CD Bioparticles offers target-specific MRI contrast agents based on both gadolinium-chelate and iron oxide nanoparticles. Scientists in CD Bioparticles are proficient in design targeted nanoparticles as contrast agents for preclinical MRI. In addition, multimodal imaging contrast probes for MRI-optical and MRI-PET can be constructed to fit for your unique requirement. <\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>References<br> Yan, G. P., Robinson, L., &amp; Hogg, P. (2007). Magnetic resonance imaging contrast agents: overview and perspectives. Radiography, 13, e5-e19.<br> Narayan, R. (2018). Encyclopedia of biomedical engineering. Elsevier. <\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Magnetic resonance imaging (MRI) is a scan that uses a strong magnetic field and radio waves to generate detailed images<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,6],"tags":[83],"class_list":["post-324","post","type-post","status-publish","format-standard","hentry","category-applications","category-magnetic-beads","tag-contrast-agents"],"_links":{"self":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/324","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/comments?post=324"}],"version-history":[{"count":1,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/324\/revisions"}],"predecessor-version":[{"id":326,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/324\/revisions\/326"}],"wp:attachment":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/media?parent=324"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/categories?post=324"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/tags?post=324"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}