{"id":277,"date":"2021-05-31T03:40:44","date_gmt":"2021-05-31T08:40:44","guid":{"rendered":"https:\/\/www.cd-bioparticles.com\/blog\/?p=277"},"modified":"2021-05-31T03:40:44","modified_gmt":"2021-05-31T08:40:44","slug":"do-you-need-gold-nanostars","status":"publish","type":"post","link":"https:\/\/www.cd-bioparticles.com\/blog\/nanoparticles\/do-you-need-gold-nanostars\/","title":{"rendered":"Do You Need Gold Nanostars?"},"content":{"rendered":"\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"321\" src=\"\/blog\/wp-content\/uploads\/2021\/05\/Gold-nanostars-in-lab-on-chip-platforms-1024x321.jpg\" alt=\"\" class=\"wp-image-278\" srcset=\"\/blog\/wp-content\/uploads\/2021\/05\/Gold-nanostars-in-lab-on-chip-platforms-1024x321.jpg 1024w, \/blog\/wp-content\/uploads\/2021\/05\/Gold-nanostars-in-lab-on-chip-platforms-300x94.jpg 300w, \/blog\/wp-content\/uploads\/2021\/05\/Gold-nanostars-in-lab-on-chip-platforms-768x241.jpg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>Over the past few years, <a href=\"https:\/\/www.cd-bioparticles.com\/product\/nanostars-list-230.html\">gold\nnanostars<\/a> have gained significant relevance in biology and medicine, in\nparticular, in imaging and photothermal therapy, also owing to their\nbiocompatibility. Furthermore, they have improved the sensitivity of diagnostic\nassays and have been integrated in <a>lab-on-chip<\/a>\nplatforms for low-cost, field-deployable devices. So, what are gold nanostars?<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>What are\ngold nanostars?<\/li><\/ol>\n\n\n\n<p>Gold Nanostars (GNS) have attracted tremendous attention\ntoward themselves owing to their multi-branched structure and unique\nproperties. These state of the art metallic nanoparticles possess intrinsic\nfeatures like remarkable optical properties and exceptional physiochemical\nactivities. These star-shaped gold nanoparticles can predominantly be utilized\nin biosensing, photothermal therapy, imaging, surface-enhanced Raman\nspectroscopy and target drug delivery applications due to their low toxicity\nand extraordinary optical features.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>How do\nnanostars work?<\/li><\/ul>\n\n\n\n<p>Nanostars are synthesized so that they absorb light in the\nnear-infrared region approximately 665\u00b19.7 nm with an average hydrodynamic\ndiameter of 66.3\u00b17.8 nm. The synthesis and characterization by\nultraviolet-visible absorption spectroscopy, dynamic light scattering, and\ntransmission electron microscopy have been described previously.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>How to\nsynthesize gold nanostars?<\/li><\/ul>\n\n\n\n<p>Gold nanostars with tunable morphology were synthesized by\na seed-mediated growth method using poly(diallyldimethylammonium chloride)\n(PDDA) as stabilizer. The number and length of the branches of the nanostars\ncan be controlled by adjusting the amount of silver nitrate. In addition, the\nAuNSs exhibit an excellent catalytic effect toward the reduction of hydrogen\nperoxide (H2O2) in deoxygenated phosphate buffer (pH 7.0). Thus, the\nPDDA-protected AuNSs were utilized to modify glassy carbon electrode directly\nfor fabricating non-enzymatic H2O2 sensor. The fast amperometric response, low\ndetection limit, wide linear range, good selectivity and long-term stability\nfor the electrochemical detection of H2O2 imply a good performance of the AuNSs\nbased sensor.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Where gold\nnanostars can be found?<\/li><\/ul>\n\n\n\n<p>Gold nanostars have unique optical properties compared to spherical gold nanoparticles of the same core diameter. The spiky uneven surface causes a red shift in the surface plasmon peak and a larger enhancement of the electromagnetic field at the tips of the gold nanostars spikes compared to that of spherical particles. Binding of ligands such as proteins to the gold nanostars surface also causes a larger shift in the surface plasmon resonance peak compared to standard spherical gold nanoparticles. This feature makes them ideal in the development of sensitive SPR-based detection assays. As a global provider of the most comprehensive list of nanoparticles products, CD Bioparticles offers a comprehensive list of functional and conjugated Nanostars, such as <a href=\"https:\/\/www.cd-bioparticles.com\/p\/Gold-Nanostars-100-nm_258_317_326_5128.html\">SpecNano\u2122 Gold Nanostars<\/a>, 100 nm(CGS-100) and SpecNano\u2122 Anti-Human IgG (H+L) Conjugated Gold Nanostars, 100 nm(CGSA-Human-100) . At CD Bioparticles, nanostars functionalized with active groups such as NHS, carboxyl, amine and hydroxyl are accessible to all researchers. Conjugated nanostars with a variety of biological ligands are also available for customers\u2019 specific requirements. <\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>References<br> Mousavi, S. M., Zarei, M., Hashemi, S. A., Ramakrishna, S., Chiang, W. H., Lai, C. W., &amp; Gholami, A. (2020). Gold nanostars-diagnosis, bioimaging and biomedical applications. Drug metabolism reviews, 52(2), 299-318.<br> D\u2019Hollander, A., Mathieu, E., Jans, H., Velde, G. V., Stakenborg, T., Van Dorpe, P., \u2026 &amp; Lagae, L. (2016). Development of nanostars as a biocompatible tumor contrast agent: toward in vivo SERS imaging. International journal of nanomedicine, 11, 3703.<br> Li, Y., Ma, J., &amp; Ma, Z. (2013). Synthesis of gold nanostars with tunable morphology and their electrochemical application for hydrogen peroxide sensing. Electrochimica Acta, 108, 435-440. <\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Over the past few years, gold nanostars have gained significant relevance in biology and medicine, in particular, in imaging and<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[75],"class_list":["post-277","post","type-post","status-publish","format-standard","hentry","category-nanoparticles","tag-gold-nanostars"],"_links":{"self":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/277","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/comments?post=277"}],"version-history":[{"count":1,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/277\/revisions"}],"predecessor-version":[{"id":279,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/277\/revisions\/279"}],"wp:attachment":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/media?parent=277"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/categories?post=277"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/tags?post=277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}