{"id":124,"date":"2020-03-31T01:48:35","date_gmt":"2020-03-31T06:48:35","guid":{"rendered":"https:\/\/www.cd-bioparticles.com\/blog\/?p=124"},"modified":"2020-03-31T01:48:35","modified_gmt":"2020-03-31T06:48:35","slug":"nanomedicine-is-becoming-a-new-favorite-in-the-pharmaceutical-field","status":"publish","type":"post","link":"https:\/\/www.cd-bioparticles.com\/blog\/nanoparticles\/nanomedicine-is-becoming-a-new-favorite-in-the-pharmaceutical-field\/","title":{"rendered":"Nanomedicine is Becoming A New Favorite in the Pharmaceutical Field"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/blog\/wp-content\/uploads\/2020\/03\/Nanomedicine-is-Becoming-A-New-Favorite-in-the-Pharmaceutical-Field-1-1024x683.jpg\" alt=\"\" class=\"wp-image-125\" srcset=\"\/blog\/wp-content\/uploads\/2020\/03\/Nanomedicine-is-Becoming-A-New-Favorite-in-the-Pharmaceutical-Field-1-1024x683.jpg 1024w, \/blog\/wp-content\/uploads\/2020\/03\/Nanomedicine-is-Becoming-A-New-Favorite-in-the-Pharmaceutical-Field-1-300x200.jpg 300w, \/blog\/wp-content\/uploads\/2020\/03\/Nanomedicine-is-Becoming-A-New-Favorite-in-the-Pharmaceutical-Field-1-768x512.jpg 768w, \/blog\/wp-content\/uploads\/2020\/03\/Nanomedicine-is-Becoming-A-New-Favorite-in-the-Pharmaceutical-Field-1-120x80.jpg 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n\n<p>Nanomedicine\ncan be broadly defined as the application of nanomaterials in improving human\nhealth. This includes the development of medical early diagnosis and prevention\napplications, and improvements in the diagnosis, treatment, and follow-up of\nmany life-threatening diseases, including cancer, cardiovascular disease,\ndiabetes, AIDS, Alzheimer&#8217;s disease, Parkinson&#8217;s disease, and various\ninflammation and infectious diseases.<\/p>\n\n\n\n<p>The size range\nof nanomaterials is 1 to 100nm, which is similar to that of basic biomaterials\nsuch as DNA, but the surface area is greatly increased, and its applications\nrange from drug and gene delivery to biomedical imaging.<\/p>\n\n\n\n<p>Nano-drugs have\nthe characteristics of small particles, large specific surface area, high\nsurface reaction activity, plenty of active sites, strong adsorption capacity\nand so on. The use of nanomaterials as drug carriers can improve the absorption\nand utilization of drugs, achieve efficient targeting delivery, prolong the\nhalf-life of drug consumption, and reduce harmful side effects on normal\ntissues.<\/p>\n\n\n\n<p>The development\nformula of nano-drug particles includes polymer nanoparticles, micelles,\nliposomes, dendrimers, metal nanoparticles, solid lipid nanoparticles and so\non. In 1995, researchers announced the first liposome-based nano-drug\nDoxorubicin, for the treatment of tumors. Today, due to the rapid development\nof science, about 50 kinds of drugs based on nanoparticles have been developed.<\/p>\n\n\n\n<p>The interaction\nbetween nano-drugs and biotic environment (molecular, cell, organ, etc.) is\nbased on a series of complex interactions between particles and biological\nmedia. Each biotic environment is unique, and the particle size, shape,\narrangement, surface charge distribution and surface chemistry of nanoparticles\nare the key factors to determine the reaction efficiency of nano-drugs with\ntheir surrounding media.<\/p>\n\n\n\n<p>Nano-drugs are\nmainly affected by three factors: biodistribution characteristics, cell uptake\nrate and the mechanism of final tissue clearance. The size of the drug\ndetermines how it is removed by the body. Particles smaller than 10nm are\nremoved by the kidney, while particles larger than 10nm are eliminated through\nthe liver and mononuclear phagocytic system.<\/p>\n\n\n\n<p>Sales of\nnanostructure applications in the life sciences, such as <a href=\"https:\/\/www.cd-bioparticles.com\/product\/nanoparticles-list-4.html\">nanoparticles<\/a>,\nnanospheres, nanocapsules, and <a href=\"https:\/\/www.cd-bioparticles.com\/product\/quantum-dots-list-169.html\">quantum\ndots<\/a>, are expected to continue to grow over the next five years, BCC\nResearch reported. The global market for life science nanostructure\napplications is expected to reach $33.8 billion by 2024 and is expected to grow\nat a CAGR of 13.7% over the next five years.<\/p>\n\n\n\n<p>Take gold\nnanoparticles as an example<\/p>\n\n\n\n<p>Nano-carriers\nhave the ability to improve the enhanced permeability and retention effect\n(EPR) of tumor tissues. In addition, nano-drugs have the following advantages:\nloading multiple drugs to play a combined therapeutic role of drugs; targeted\ndelivery of specific drugs to tumor cells and tumor microenvironment;\nsimultaneous visualization of tumor therapeutic effects based on new imaging\ntechniques; prolonging drug circulation time; controlling drug release;\noptimizing treatment regimens to improve patient compliance.<\/p>\n\n\n\n<p>A particularly\nactive area of nanomedical research is the design of <a href=\"https:\/\/www.cd-bioparticles.com\/product\/functional-gold-nanoparticles-list-178.html\">functionalized\ngold nanoparticles<\/a> as multi-purpose agents for biomedical imaging and drug\ndelivery. Gold nanoparticles are known for their strong optical activity at\nvisible to near-infrared (NIR) wavelengths and are being actively studied\ncontrast agents for optical imaging modes.<\/p>\n\n\n\n<p>Due to the new\nprogress in the scalable synthesis of anisotropic gold nanoparticles, a new\nround of research on gold nanoparticles is underway. For example, <a href=\"https:\/\/www.cd-bioparticles.com\/product\/gold-nanorods-list-165.html\">gold\nnanorods<\/a> (GNRs), with a much shorter length than 100nm can be prepared and\ntheir efficient NIR absorptivity can greatly improve the range of medical\noptical effectiveness modes, such as optical coherence tomography (OCT) and\nphotoacoustic tomography (PAT).<\/p>\n\n\n\n<p>However, gold\nnanoparticles are not only passive imaging agents and carriers: most of the\nphotons absorbed by gold nanoparticles are converted into heat, resulting in a\nstrong photothermal effect. At high gold nanoparticles concentration and high\nlaser power, these photothermal effects can produce milder high-temperature\nwith lower power irradiation, resulting in ablation of nearby cells and tissues\nand enhancing the therapeutic effect in a more subtle way. These effects\nstimulate the new concept of nanomedicine, in which photothermal effect\ncombined with diagnostic imaging or drugs leads to a new type of combined\ntherapy.<\/p>\n\n\n\n<p>In addition,\nadvances in supporting technologies such as microfluidic technology and 3D\nprinting may help the nanomedical industry to achieve cheap and standardized\nfluid devices in the future. It also opens up possibilities for new\napplications in the fields of personalized medicine, drug production, and\nwearable technology.\n\nThere is no doubt that nanomedicine has the\nopportunity to bring better health care results. By 2025, the market for\nnanomedicine could reach $350.8 billion. According to another Market Research\nEngine report, the European drug delivery market will reach $536 billion by\n2024.\n\n\n\n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nanomedicine can be broadly defined as the application of nanomaterials in improving human health. This includes the development of medical<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,2],"tags":[8,28,5,10],"class_list":["post-124","post","type-post","status-publish","format-standard","hentry","category-applications","category-nanoparticles","tag-gold-nanoparticles","tag-gold-nanorods","tag-nanoparticles","tag-quantum-dots"],"_links":{"self":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/124","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/comments?post=124"}],"version-history":[{"count":1,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/124\/revisions"}],"predecessor-version":[{"id":126,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/posts\/124\/revisions\/126"}],"wp:attachment":[{"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/media?parent=124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/categories?post=124"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cd-bioparticles.com\/blog\/wp-json\/wp\/v2\/tags?post=124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}